The Collaborative Institutional Training Initiative platform (CITI Program) has updated its Good Clinical Practice (GCP) modules to align with the ICH E6(R3) guidelines and the recently released final guidance from the Food and Drug Administration (FDA) for E6(R3) Good Clinical Practice. The E6(R3) updates have been applied to all relevant CITI modules as of July 23, 2025, previously completed modules can be reviewed and re-completed to remain in compliance with the ICH GCP E6(R3) updates. New enrollees will automatically receive updated content. Please direct any questions or concerns to support@citiprogram.org.